Abstract
A method was developed for quantitating the temperature within frozen tissue with the magnetic resonance (MR) parameter R2*. The pulse sequence uses half-pulse excitation and a short spiral readout to achieve echo times as short as 0.2 msec. Fiber-optic temperature sensors were inserted into bovine liver tissue. The tissue was frozen at one end while being held warm at the other end. Once steady state was reached, the parameter R2* was measured. A linear dependence of R2* on temperature was demonstrated. R2* is independent of freeze number and of the orientation of the temperature gradient with respect to the main magnetic field. Feasibility in a canine prostate during cryosurgery is demonstrated.
Original language | English (US) |
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Pages (from-to) | 99-104 |
Number of pages | 6 |
Journal | Journal of Magnetic Resonance Imaging |
Volume | 13 |
Issue number | 1 |
DOIs | |
State | Published - 2001 |
Externally published | Yes |
Keywords
- Cryosurgery
- Frozen tissue
- Image-guided therapy
- Magnetic resonance imaging
- R2*
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging