Technical considerations in brain amyloid PET imaging with 18F-Florbetapir

LisaAnn Trembath, Maureen Newell, Michael D. Devous

Research output: Contribution to journalArticlepeer-review

19 Scopus citations


Technical factors play a critical role in the production of best-quality amyloid PET images for interpretation. This article provides specific instructions and general technical information about PET brain scanning of ß-amyloid neuritic plaques. The focus of tracer-specific information will be on 18F-florbetapir (indications, contraindications, dosing, administration, uptake time, scanning time, acquisition, processing, biodistribution, radiation dose, adverse events, and display). General scanning information relevant to all amyloid-imaging agents will be also be presented (e.g., mechanism of uptake, safe handling, positioning, prevention of patient motion, processing, and artifacts).

Original languageEnglish (US)
Pages (from-to)175-184
Number of pages10
JournalJournal of nuclear medicine technology
Issue number3
StatePublished - 2015


  • Amyloid
  • Brain imaging
  • Florbetapir
  • PET
  • Technical

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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