TCF3, TCF12 and distinct enhancers regulate oocyte transcription

Qiqi Cao; Edward J. Grow

doi:10.1038/s41556-024-01433-8

TCF3, TCF12 and distinct enhancers regulate oocyte transcription

Research output: Contribution to journal › Comment/debate › peer-review

Abstract

Oocyte development involves the prolonged and intricate process of building a distinctive transcriptome and epigenome to anticipate embryogenesis after fertilization. Research now shows that mouse oocytes use an unusual chromatin signature to mark regulatory elements, and that the transcription factors TCF3 and TCF12 have a key role.

Original language	English (US)
Pages (from-to)	847-848
Number of pages	2
Journal	Nature cell biology
Volume	26
Issue number	6
DOIs	https://doi.org/10.1038/s41556-024-01433-8
State	Published - Jun 2024

ASJC Scopus subject areas

Cell Biology

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title = "TCF3, TCF12 and distinct enhancers regulate oocyte transcription",

abstract = "Oocyte development involves the prolonged and intricate process of building a distinctive transcriptome and epigenome to anticipate embryogenesis after fertilization. Research now shows that mouse oocytes use an unusual chromatin signature to mark regulatory elements, and that the transcription factors TCF3 and TCF12 have a key role.",

author = "Qiqi Cao and Grow, {Edward J.}",

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TCF3, TCF12 and distinct enhancers regulate oocyte transcription

Abstract

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