Targeted expression of teashirt induces ectopic eyes in Drosophila

Duojia Pan, Gerald M. Rubin

Research output: Contribution to journalArticlepeer-review

80 Scopus citations


teashirt was initially identified as a gene required for the specification of the trunk segments in Drosophila embryogenesis and encodes a transcription factor with zinc finger motifs. We report here that targeted expression of teashirt in imaginal discs is sufficient to induce ectopic eye formation in non-eye tissues, a phenotype similar to that produced from targeted expression of eyeless, dachshund, and eyes absent. Furthermore, teashirt and eyeless induce the expression of each other, suggesting that teashirt is part of the gene network that functions to specify eye identity.

Original languageEnglish (US)
Pages (from-to)15508-15512
Number of pages5
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number26
StatePublished - Dec 22 1998

ASJC Scopus subject areas

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