T-cell receptor ligation by peptide/MHC induces activation of a caspase in immature thymocytes: The molecular basis of negative selection

Medicine & Life Sciences

• Thymocytes 84%
• T-Cell Antigen Receptor 79%
• Caspases 78%
• Ligation 68%
• Peptides 49%
• Organ Culture Techniques 26%
• Gene Rearrangement 13%
• Inbred C57BL Mouse 10%
• Transgenic Mice 9%
• Adrenal Cortex Hormones 8%
• Cell Death 8%
• Monoclonal Antibodies 8%
• Ligands 7%
• Antigens 7%
• Apoptosis 6%

Chemical Compounds

• Adrenal Cortex Hormone 100%
• Apoptotic 89%
• Cell Death 83%
• Enzyme Activity 64%
• Peptide 45%
• Ligand 34%