TY - JOUR
T1 - Systemic Diseases with Renal Manifestations
AU - Rajashekar, Asha
AU - Perazella, Mark A.
AU - Crowley, Susan
N1 - Funding Information:
This work was supported by the Yale Nephrology Section.
Copyright:
Copyright 2008 Elsevier B.V., All rights reserved.
PY - 2008/6
Y1 - 2008/6
N2 - This article discusses the epidemiology, recognition, screening, and management of six systemic diseases that commonly present with renal manifestations: diabetic nephropathy, lupus nephritis, congestive heart failure, HIV, liver disease, and dysproteinemias. Diabetic nephropathy remains the leading cause of end-stage renal disease in the United States. The outlook for patients who have lupus nephritis and HIV-associated nephropathy has improved in the last decade. Kidney disease is common in patients who have advanced liver disease, and creatinine-based methods do not provide an accurate estimation of renal function in this population. Dysproteinemias are associated with protean renal manifestations, and renal disease may be the presenting manifestation.
AB - This article discusses the epidemiology, recognition, screening, and management of six systemic diseases that commonly present with renal manifestations: diabetic nephropathy, lupus nephritis, congestive heart failure, HIV, liver disease, and dysproteinemias. Diabetic nephropathy remains the leading cause of end-stage renal disease in the United States. The outlook for patients who have lupus nephritis and HIV-associated nephropathy has improved in the last decade. Kidney disease is common in patients who have advanced liver disease, and creatinine-based methods do not provide an accurate estimation of renal function in this population. Dysproteinemias are associated with protean renal manifestations, and renal disease may be the presenting manifestation.
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U2 - 10.1016/j.pop.2008.01.006
DO - 10.1016/j.pop.2008.01.006
M3 - Review article
C2 - 18486717
AN - SCOPUS:43649098164
SN - 0095-4543
VL - 35
SP - 297
EP - 328
JO - Primary Care - Clinics in Office Practice
JF - Primary Care - Clinics in Office Practice
IS - 2
ER -