Abstract
A questionnaire that was mailed to 510 randomly selected dermatologists in the United States surveyed their use of three systemic chemotherapeutic agents for the treatment of psoriasis during the two-year period of 1973 to 1974. Methotrexate was used by 52% of the surveyed dermatologists, while hydroxyurea and azaribine were used by 10% and 2%, respectively. Seventy-five percent of the dermatologists who used methotrexate treated ten or fewer psoriatic patients with this drug. Multiple dose therapy with methotrexate divided over a period of 36 hours each week was the preferred schedule of 66% of the dermatologists. Liver biopsy specimens and creatinine clearance tests were obtained for only 17% and 35% of patients, respectively, prior to initiating methotrexate therapy. The estimated number of dermatologisttreated psoriatics nationwide receiving methotrexate is 25,000.
Original language | English (US) |
---|---|
Pages (from-to) | 977-981 |
Number of pages | 5 |
Journal | Archives of Dermatology |
Volume | 112 |
Issue number | 7 |
DOIs | |
State | Published - Jul 1976 |
ASJC Scopus subject areas
- Dermatology