An efficient entry into densely substituted fluorinated and perfluoroalkylated benzene derivatives via chemo- and regioselective Pd-catalyzed [4 + 2] cross-benzannulation is presented. The synthetic utility of these products for the synthesis of various aromatic and heteroaromatic compounds is also demonstrated. This strategy offers a viable and quite general alternative to existing fluorination and perfluoroalkylation methods for securing these valuable molecules.
|Original language||English (US)|
|Number of pages||4|
|State||Published - May 17 2013|
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry