Synaptic vesicle fusion without SNARE transmembrane regions

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations


Diverse roles in membrane fusion have been proposed for the transmembrane regions (TMRs) of SNARE proteins, including formation of channel-like transmembrane pores. Reporting in Neuron, Zhou etal. (2013) show that lipid-anchored SNAREs lacking TMRs can support neurotransmitter release, suggesting that SNAREs function primarily as power engines that force membranes together.

Original languageEnglish (US)
Pages (from-to)124-126
Number of pages3
JournalDevelopmental cell
Issue number2
StatePublished - Oct 28 2013

ASJC Scopus subject areas

  • Molecular Biology
  • Biochemistry, Genetics and Molecular Biology(all)
  • Developmental Biology
  • Cell Biology


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