Abstract
Diverse roles in membrane fusion have been proposed for the transmembrane regions (TMRs) of SNARE proteins, including formation of channel-like transmembrane pores. Reporting in Neuron, Zhou etal. (2013) show that lipid-anchored SNAREs lacking TMRs can support neurotransmitter release, suggesting that SNAREs function primarily as power engines that force membranes together.
Original language | English (US) |
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Pages (from-to) | 124-126 |
Number of pages | 3 |
Journal | Developmental cell |
Volume | 27 |
Issue number | 2 |
DOIs | |
State | Published - Oct 28 2013 |
ASJC Scopus subject areas
- Molecular Biology
- Biochemistry, Genetics and Molecular Biology(all)
- Developmental Biology
- Cell Biology