Synaptic vesicle fusion without SNARE transmembrane regions

Jose Rizo-Rey; Junjie Xu

doi:10.1016/j.devcel.2013.10.010

Synaptic vesicle fusion without SNARE transmembrane regions

Jose Rizo-Rey, Junjie Xu

Research output: Contribution to journal › Short survey › peer-review

4 Scopus citations

Abstract

Diverse roles in membrane fusion have been proposed for the transmembrane regions (TMRs) of SNARE proteins, including formation of channel-like transmembrane pores. Reporting in Neuron, Zhou etal. (2013) show that lipid-anchored SNAREs lacking TMRs can support neurotransmitter release, suggesting that SNAREs function primarily as power engines that force membranes together.

Original language	English (US)
Pages (from-to)	124-126
Number of pages	3
Journal	Developmental cell
Volume	27
Issue number	2
DOIs	https://doi.org/10.1016/j.devcel.2013.10.010
State	Published - Oct 28 2013

ASJC Scopus subject areas

Molecular Biology
General Biochemistry, Genetics and Molecular Biology
Developmental Biology
Cell Biology

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10.1016/j.devcel.2013.10.010

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title = "Synaptic vesicle fusion without SNARE transmembrane regions",

abstract = "Diverse roles in membrane fusion have been proposed for the transmembrane regions (TMRs) of SNARE proteins, including formation of channel-like transmembrane pores. Reporting in Neuron, Zhou etal. (2013) show that lipid-anchored SNAREs lacking TMRs can support neurotransmitter release, suggesting that SNAREs function primarily as power engines that force membranes together.",

author = "Jose Rizo-Rey and Junjie Xu",

year = "2013",

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doi = "10.1016/j.devcel.2013.10.010",

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journal = "Developmental cell",

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AU - Xu, Junjie

PY - 2013/10/28

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AB - Diverse roles in membrane fusion have been proposed for the transmembrane regions (TMRs) of SNARE proteins, including formation of channel-like transmembrane pores. Reporting in Neuron, Zhou etal. (2013) show that lipid-anchored SNAREs lacking TMRs can support neurotransmitter release, suggesting that SNAREs function primarily as power engines that force membranes together.

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Synaptic vesicle fusion without SNARE transmembrane regions

Abstract

ASJC Scopus subject areas

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