TY - JOUR
T1 - Surgical management of hepatocellular carcinoma
T2 - Resection and ablation
AU - Choti, Michael A.
N1 - Copyright:
Copyright 2021 Elsevier B.V., All rights reserved.
PY - 2002/9/1
Y1 - 2002/9/1
N2 - In this article, the author reviews the recent advances in the surgical management of hepatocellular carcinoma (HCC). Partial hepatic resection or, in some instances, liver transplantation provides the best chance for cure. Risk of perioperative mortality after partial hepatectomy is less than 5% in most experienced centers. Careful preoperative assessment of hepatic function is important to reduce the risk of postoperative liver failure after liver resection. Long-term outcomes after resection are comparable to those with liver transplantation, with reported 5-year survival rates of 25%-50%. Although limited controlled comparative studies exist, surgical and nonsurgical local ablative therapies, including ethanol and radiofrequency ablation, may result in survival benefit.
AB - In this article, the author reviews the recent advances in the surgical management of hepatocellular carcinoma (HCC). Partial hepatic resection or, in some instances, liver transplantation provides the best chance for cure. Risk of perioperative mortality after partial hepatectomy is less than 5% in most experienced centers. Careful preoperative assessment of hepatic function is important to reduce the risk of postoperative liver failure after liver resection. Long-term outcomes after resection are comparable to those with liver transplantation, with reported 5-year survival rates of 25%-50%. Although limited controlled comparative studies exist, surgical and nonsurgical local ablative therapies, including ethanol and radiofrequency ablation, may result in survival benefit.
KW - Liver neoplasms, therapeutic radiology
KW - Liver, surgery
UR - http://www.scopus.com/inward/record.url?scp=0036741688&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0036741688&partnerID=8YFLogxK
U2 - 10.1016/s1051-0443(07)61787-4
DO - 10.1016/s1051-0443(07)61787-4
M3 - Review article
C2 - 12354837
AN - SCOPUS:0036741688
SN - 1051-0443
VL - 13
SP - S197-S203
JO - Journal of Vascular and Interventional Radiology
JF - Journal of Vascular and Interventional Radiology
IS - 9 II
ER -