Surface energy induced patterning of polymer nanostructures for cancer diagnosis and therapy

Wenchuang Hu; Fern Yoon; Adam Crouch; Li Tao; Heather Hillebrenner; Jagadeesh Setti Guthi; Moon Kim; Jinming Gao

doi:10.1109/NANO.2007.4601193

Surface energy induced patterning of polymer nanostructures for cancer diagnosis and therapy

Wenchuang Hu, Fern Yoon, Adam Crouch, Li Tao, Heather Hillebrenner, Jagadeesh Setti Guthi, Moon Kim, Jinming Gao

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

1 Scopus citations

Abstract

We have developed a new simple method to pattern discrete polymer micro and nanostructures. A Si template is patterned by lithography and selective surface treatment to have spatially different surface energies that induce microfluidic self-patterning of a spincoated polymer layer. Biocompatible diblock co-polymer and SU8 are patterned using this method to form monodisperse and shape specific microstructures. After patterning, these particles are lifted off the template surface into aqueous solution. The template is then cleaned and re-used. These freestanding polymer particles with uniform and precise spherical morphology can be used as carriers for drug and imaging agents for biomedical applications.

Original language	English (US)
Title of host publication	2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings
Pages	295-299
Number of pages	5
DOIs	https://doi.org/10.1109/NANO.2007.4601193
State	Published - 2007
Event	2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007 - Hong Kong, China Duration: Aug 2 2007 → Aug 5 2007

Publication series

Name	2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings

Other

Other	2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007
Country/Territory	China
City	Hong Kong
Period	8/2/07 → 8/5/07

ASJC Scopus subject areas

Electrical and Electronic Engineering
Atomic and Molecular Physics, and Optics

Access to Document

10.1109/NANO.2007.4601193

Cite this

Hu, W., Yoon, F., Crouch, A., Tao, L., Hillebrenner, H., Guthi, J. S., Kim, M., & Gao, J. (2007). Surface energy induced patterning of polymer nanostructures for cancer diagnosis and therapy. In 2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings (pp. 295-299). Article 4601193 (2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings). https://doi.org/10.1109/NANO.2007.4601193

Surface energy induced patterning of polymer nanostructures for cancer diagnosis and therapy. / Hu, Wenchuang; Yoon, Fern; Crouch, Adam et al.
2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings. 2007. p. 295-299 4601193 (2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Hu, W, Yoon, F, Crouch, A, Tao, L, Hillebrenner, H, Guthi, JS, Kim, M & Gao, J 2007, Surface energy induced patterning of polymer nanostructures for cancer diagnosis and therapy. in 2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings., 4601193, 2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings, pp. 295-299, 2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Hong Kong, China, 8/2/07. https://doi.org/10.1109/NANO.2007.4601193

Hu W, Yoon F, Crouch A, Tao L, Hillebrenner H, Guthi JS et al. Surface energy induced patterning of polymer nanostructures for cancer diagnosis and therapy. In 2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings. 2007. p. 295-299. 4601193. (2007 7th IEEE International Conference on Nanotechnology - IEEE-NANO 2007, Proceedings). doi: 10.1109/NANO.2007.4601193

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abstract = "We have developed a new simple method to pattern discrete polymer micro and nanostructures. A Si template is patterned by lithography and selective surface treatment to have spatially different surface energies that induce microfluidic self-patterning of a spincoated polymer layer. Biocompatible diblock co-polymer and SU8 are patterned using this method to form monodisperse and shape specific microstructures. After patterning, these particles are lifted off the template surface into aqueous solution. The template is then cleaned and re-used. These freestanding polymer particles with uniform and precise spherical morphology can be used as carriers for drug and imaging agents for biomedical applications.",

author = "Wenchuang Hu and Fern Yoon and Adam Crouch and Li Tao and Heather Hillebrenner and Guthi, {Jagadeesh Setti} and Moon Kim and Jinming Gao",

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AB - We have developed a new simple method to pattern discrete polymer micro and nanostructures. A Si template is patterned by lithography and selective surface treatment to have spatially different surface energies that induce microfluidic self-patterning of a spincoated polymer layer. Biocompatible diblock co-polymer and SU8 are patterned using this method to form monodisperse and shape specific microstructures. After patterning, these particles are lifted off the template surface into aqueous solution. The template is then cleaned and re-used. These freestanding polymer particles with uniform and precise spherical morphology can be used as carriers for drug and imaging agents for biomedical applications.

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Surface energy induced patterning of polymer nanostructures for cancer diagnosis and therapy

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