Abstract
A patient with gestational trophoblastic neoplasm failed treatment with several standard chemotherapy regimens and had progressive disease with development of lung and brain metastases and a rising HCG level. Following resection of the metastases and whole-brain radiotherapy she was treated with high-dose etoposide and cyclophosphamide. She promptly attained a complete remission and remains free of disease 15 months after completion of therapy. This regimen, although initially developed for leukemia and lymphoma treatment, has potential as a therapy for refractory gestational trophoblastic neoplasm because it delivers high doses of agents very active in this disease.
Original language | English (US) |
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Pages (from-to) | 317-319 |
Number of pages | 3 |
Journal | Gynecologic oncology |
Volume | 43 |
Issue number | 3 |
DOIs | |
State | Published - Dec 1991 |
ASJC Scopus subject areas
- Oncology
- Obstetrics and Gynecology