Successful Pregnancy in a Patient with Sheehan's Syndrome

J. E. Martin, P. C. MacDonald, Norman M Kaplan

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


During the 16 years after a massive post-partum hemorrhage attended by coma, a patient had only occasional menses but went through three uneventful pregnancies. In the fourth month of her fourth pregnancy, there were both clinical and laboratory features of decreased thyroidal and adrenal function, which improved on hormonal replacement therapy. Tests done three months after delivery revealed decreased pituitary secretory capacity for ACTH, TSH and growth hormone. Although some pituitary-function tests may be contraindicated or unreliable in pregnancy, partial pituitary deficiency may be recognized and treated appropriately.

Original languageEnglish (US)
Pages (from-to)425-427
Number of pages3
JournalNew England Journal of Medicine
Issue number8
StatePublished - Feb 19 1970

ASJC Scopus subject areas

  • Medicine(all)


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