Success for gene therapy: Render unto Caesar that which is Caesar's

Jian Qiao; Rosa Maria Diaz; Richard G. Vile

doi:10.1186/gb-2004-5-8-237

Success for gene therapy: Render unto Caesar that which is Caesar's

Jian Qiao, Rosa Maria Diaz, Richard G. Vile

Research output: Contribution to journal › Short survey › peer-review

3 Scopus citations

Abstract

Reports that two young children developed leukemia after being treated for immunodeficiency with their own retrovirally modified bone-marrow cells delivered a severe blow to confidence in gene therapy as a treatment. Two reports, published since the trial was initiated, now take away some of the mystery as to why these events happened and allay fears for the safety of gene therapy across all therapeutic applications.

Original language	English (US)
Article number	237
Journal	Genome biology
Volume	5
Issue number	8
DOIs	https://doi.org/10.1186/gb-2004-5-8-237
State	Published - 2004

ASJC Scopus subject areas

Ecology, Evolution, Behavior and Systematics
Genetics
Cell Biology

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10.1186/gb-2004-5-8-237

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title = "Success for gene therapy: Render unto Caesar that which is Caesar's",

abstract = "Reports that two young children developed leukemia after being treated for immunodeficiency with their own retrovirally modified bone-marrow cells delivered a severe blow to confidence in gene therapy as a treatment. Two reports, published since the trial was initiated, now take away some of the mystery as to why these events happened and allay fears for the safety of gene therapy across all therapeutic applications.",

author = "Jian Qiao and Diaz, {Rosa Maria} and Vile, {Richard G.}",

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AU - Qiao, Jian

AU - Diaz, Rosa Maria

AU - Vile, Richard G.

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N2 - Reports that two young children developed leukemia after being treated for immunodeficiency with their own retrovirally modified bone-marrow cells delivered a severe blow to confidence in gene therapy as a treatment. Two reports, published since the trial was initiated, now take away some of the mystery as to why these events happened and allay fears for the safety of gene therapy across all therapeutic applications.

AB - Reports that two young children developed leukemia after being treated for immunodeficiency with their own retrovirally modified bone-marrow cells delivered a severe blow to confidence in gene therapy as a treatment. Two reports, published since the trial was initiated, now take away some of the mystery as to why these events happened and allay fears for the safety of gene therapy across all therapeutic applications.

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DO - 10.1186/gb-2004-5-8-237

M3 - Short survey

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SN - 1465-6906

VL - 5

JO - Genome biology

JF - Genome biology

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ER -

Success for gene therapy: Render unto Caesar that which is Caesar's

Abstract

ASJC Scopus subject areas

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