Studying Lineage Plasticity One Cell at a Time

Research output: Contribution to journalComment/debatepeer-review

5 Scopus citations


The development and consequences of lineage plasticity during tumorigenesis have remained mysterious due to the limits of single-cell analysis. In this issue of Cancer Cell, LaFave et al. and Marjanovic et al. identify highly plastic subpopulations within lung adenocarcinoma that may underlie intratumoral lineage heterogeneity, metastasis, and acquired resistance to chemotherapy.

Original languageEnglish (US)
Pages (from-to)150-152
Number of pages3
JournalCancer Cell
Issue number2
StatePublished - Aug 10 2020

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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