Abstract
At the present time, knowledge of the structure of the proton-translocating ATPase responsible for urinary acidification is far from complete. Key issues awaiting resolution are full definition of sub-unit structure and an understanding of the interactions among functional domains of this complex hetero-oligomer. Such a detailed analysis is required to begin study of the biogenesis of the vacuolar proton pump and to elucidate the complexities of its molecular regulation.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 159-165 |
| Number of pages | 7 |
| Journal | Seminars in nephrology |
| Volume | 10 |
| Issue number | 2 |
| State | Published - Mar 1990 |
ASJC Scopus subject areas
- Nephrology