Abstract
The crystalline β-From the sodium salt of poly d(A) poly d(U) trapped in oriented fibers forms a Watson-Crick base-paired, 101 double-helix of pitch 3.2 nm. Two molecules are present in a monoclinic unit cell apparently isomorphous with β-poly d(A) polyd(T). The two chains in each molecule both carry C2’-endo puckered furanose rings but are conformationally not identical. The orientations of the A: U base-pairs relative to the helix-axis are distinctly different from those in classical B-DNA and the overall morphology of the duplex in which they reside resembles that of the a-forms of poly (purine)· poly (pyrimidine) DNA duplexes previously reported.
Original language | English (US) |
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Pages (from-to) | 1203-1215 |
Number of pages | 13 |
Journal | Journal of Biomolecular Structure and Dynamics |
Volume | 6 |
Issue number | 6 |
DOIs | |
State | Published - Jun 1989 |
ASJC Scopus subject areas
- Structural Biology
- Molecular Biology