Structure of (-)-neodysidenin from Dysidea herbacea. Implications for biosynthesis of 5,5,5-trichloroleucine peptides

John B. MacMillan; Eugene K. Trousdale; Tadeusz F. Molinski

Structure of (-)-neodysidenin from Dysidea herbacea. Implications for biosynthesis of 5,5,5-trichloroleucine peptides

John B. MacMillan, Eugene K. Trousdale, Tadeusz F. Molinski

Research output: Contribution to journal › Article › peer-review

Abstract

(equation presented) Neodysidenin was isolated from the marine sponge Dysidea herbacea (Keller 1889) collected on the Great Barrier Reef. The complete configuration was obtained from a combination of methods, including capillary electrophoresis of Marfey's derivatives. Neodysidenin belongs to the L-series of trichloroleucine peptides, and the configuration of the N-methyl thiazolyl alanine residue (13R) is opposite to that of dysidenin.

Original language	English (US)
Pages (from-to)	2721-2723
Number of pages	3
Journal	Organic Letters
Volume	2
Issue number	17
State	Published - Aug 24 2000

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

Cite this

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title = "Structure of (-)-neodysidenin from Dysidea herbacea. Implications for biosynthesis of 5,5,5-trichloroleucine peptides",

abstract = "(equation presented) Neodysidenin was isolated from the marine sponge Dysidea herbacea (Keller 1889) collected on the Great Barrier Reef. The complete configuration was obtained from a combination of methods, including capillary electrophoresis of Marfey's derivatives. Neodysidenin belongs to the L-series of trichloroleucine peptides, and the configuration of the N-methyl thiazolyl alanine residue (13R) is opposite to that of dysidenin.",

author = "MacMillan, {John B.} and Trousdale, {Eugene K.} and Molinski, {Tadeusz F.}",

year = "2000",

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journal = "Organic Letters",

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T1 - Structure of (-)-neodysidenin from Dysidea herbacea. Implications for biosynthesis of 5,5,5-trichloroleucine peptides

AU - MacMillan, John B.

AU - Trousdale, Eugene K.

AU - Molinski, Tadeusz F.

PY - 2000/8/24

Y1 - 2000/8/24

N2 - (equation presented) Neodysidenin was isolated from the marine sponge Dysidea herbacea (Keller 1889) collected on the Great Barrier Reef. The complete configuration was obtained from a combination of methods, including capillary electrophoresis of Marfey's derivatives. Neodysidenin belongs to the L-series of trichloroleucine peptides, and the configuration of the N-methyl thiazolyl alanine residue (13R) is opposite to that of dysidenin.

AB - (equation presented) Neodysidenin was isolated from the marine sponge Dysidea herbacea (Keller 1889) collected on the Great Barrier Reef. The complete configuration was obtained from a combination of methods, including capillary electrophoresis of Marfey's derivatives. Neodysidenin belongs to the L-series of trichloroleucine peptides, and the configuration of the N-methyl thiazolyl alanine residue (13R) is opposite to that of dysidenin.

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AN - SCOPUS:0034710498

SN - 1523-7060

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JO - Organic Letters

JF - Organic Letters

IS - 17

ER -

Structure of (-)-neodysidenin from Dysidea herbacea. Implications for biosynthesis of 5,5,5-trichloroleucine peptides

Abstract

ASJC Scopus subject areas

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