TY - JOUR
T1 - Structure of maltoheptaose by difference Fourier methods and a model for glycogen
AU - Goldsmith, E.
AU - Sprang, S.
AU - Fletterick, R.
PY - 1982/4/5
Y1 - 1982/4/5
N2 - The structure of the glucose heptamer, maltoheptaose, has been determined by difference Fourier analysis at 0.25 nm resolution through its binding to phosphorylase a. It is a left-handed helical structure, with 6.5 glucose residues per turn and a rise per residue of 2.4 Å. The molecule shows short-range order when no protein is present to stabilize its conformation in solution. With one exception, the individual torsion angles between sugar residues vary over a narrow range and preserve a good O(2)O(3′) hydrogen bond. The length of an individual chain for glycogen can be extrapolated from the maltoheptaose data and agrees well with the size for glycogen predicted by the Whelan model.
AB - The structure of the glucose heptamer, maltoheptaose, has been determined by difference Fourier analysis at 0.25 nm resolution through its binding to phosphorylase a. It is a left-handed helical structure, with 6.5 glucose residues per turn and a rise per residue of 2.4 Å. The molecule shows short-range order when no protein is present to stabilize its conformation in solution. With one exception, the individual torsion angles between sugar residues vary over a narrow range and preserve a good O(2)O(3′) hydrogen bond. The length of an individual chain for glycogen can be extrapolated from the maltoheptaose data and agrees well with the size for glycogen predicted by the Whelan model.
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U2 - 10.1016/0022-2836(82)90336-9
DO - 10.1016/0022-2836(82)90336-9
M3 - Article
C2 - 7086906
AN - SCOPUS:0020056622
SN - 0022-2836
VL - 156
SP - 411
EP - 427
JO - Journal of Molecular Biology
JF - Journal of Molecular Biology
IS - 2
ER -