Structurally analogous proteins do exist!

S. Sri Krishna; Nick V. Grishin

doi:10.1016/j.str.2004.06.004

Structurally analogous proteins do exist!

S. Sri Krishna, Nick V. Grishin

Research output: Contribution to journal › Review article › peer-review

37 Scopus citations

Abstract

The structure of a random protein sequence selected in vitro for ATP binding (Lo Surdo et al., 2004) resembles the treble clef zinc binding motif. Since this artificial protein does not share a common ancestor with any natural treble clefs, it exemplifies the existence of structural analogs.

Original language	English (US)
Pages (from-to)	1125-1127
Number of pages	3
Journal	Structure
Volume	12
Issue number	7
DOIs	https://doi.org/10.1016/j.str.2004.06.004
State	Published - Jul 2004

ASJC Scopus subject areas

Structural Biology
Molecular Biology

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10.1016/j.str.2004.06.004

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title = "Structurally analogous proteins do exist!",

abstract = "The structure of a random protein sequence selected in vitro for ATP binding (Lo Surdo et al., 2004) resembles the treble clef zinc binding motif. Since this artificial protein does not share a common ancestor with any natural treble clefs, it exemplifies the existence of structural analogs.",

author = "Krishna, {S. Sri} and Grishin, {Nick V.}",

note = "Funding Information: We are grateful to Dr. Lo Surdo for helpful comments on our manuscript. This work was supported by NIH grant GM67165 to N.V.G.",

year = "2004",

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journal = "Structure",

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AU - Krishna, S. Sri

AU - Grishin, Nick V.

N1 - Funding Information: We are grateful to Dr. Lo Surdo for helpful comments on our manuscript. This work was supported by NIH grant GM67165 to N.V.G.

PY - 2004/7

Y1 - 2004/7

N2 - The structure of a random protein sequence selected in vitro for ATP binding (Lo Surdo et al., 2004) resembles the treble clef zinc binding motif. Since this artificial protein does not share a common ancestor with any natural treble clefs, it exemplifies the existence of structural analogs.

AB - The structure of a random protein sequence selected in vitro for ATP binding (Lo Surdo et al., 2004) resembles the treble clef zinc binding motif. Since this artificial protein does not share a common ancestor with any natural treble clefs, it exemplifies the existence of structural analogs.

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JO - Structure

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Structurally analogous proteins do exist!

Abstract

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