Structural Analysis of the MAP Kinase ERK2 and Studies of MAP Kinase Regulatory Pathways

TY - JOUR

T1 - Structural Analysis of the MAP Kinase ERK2 and Studies of MAP Kinase Regulatory Pathways

AU - Cobb, Melanie H.

AU - Xu, Shuichan

AU - Cheng, Mangeng

AU - Ebert, Doug

AU - Robbins, David

AU - Goldsmith, Elizabeth

AU - Robinson, Megan

N1 - Funding Information: We thank Jeff Frost, Jessie Hepler, Meg Phillips, Tom Geppert, and members of the Cobb lab (University of Texas Southwestern) for valuable discussions and crirical reading of the manuscript, Clark Garcia for preparation of some of the bacterial proteins, Colleen Vanderbilt for assistance with isolation of the rat MEKKl cDNA and imrnunoblotting, and Jo Hicks for preparation of the manuscript. We also thank Natalie Ahn and Sam Mansour (University of Colorado, Boulder) for the MEKl mutants used in this study. This work was supported by Grants I1243 to M.H.C. and I1128 to E.G. from the Welch Foundarion, National Institutes of Health research Grants DK34128 (M.H.C.) and DK46993 (E.G.), a Council for Tobacco Research research grant, and a fellowship from the Juvenile Diabetes Association (to S.X.).

PY - 1996

Y1 - 1996

UR - http://www.scopus.com/inward/record.url?scp=0030358762&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0030358762&partnerID=8YFLogxK

U2 - 10.1016/S1054-3589(08)60576-1

DO - 10.1016/S1054-3589(08)60576-1

M3 - Article

C2 - 8783554

AN - SCOPUS:0030358762

SN - 1054-3589

VL - 36

SP - 49

EP - 65

JO - Advances in pharmacology (San Diego, Calif.)

JF - Advances in pharmacology (San Diego, Calif.)

IS - C

ER -