Stem cells for the ischaemic heart

Thomas J. Povsic, Eric D. Peterson

Research output: Contribution to journalReview articlepeer-review


The discovery of adult progenitor cells capable of generating new vascular and myocardial tissue offers the promise of salvage of ischaemically threatened or irreversibly damaged cardiac tissue. Not surprisingly, great interest has focused on the use of a variety of cell types to treat both acute myocardial infarction and chronic ischaemic heart disease. This review focuses on the treatment of these two categories of disease, the cell types being considered, our understanding of timing and methods of cellular administration, and possible mechanisms of myocardial salvage.

Original languageEnglish (US)
Pages (from-to)427-442
Number of pages16
JournalExpert Opinion on Biological Therapy
Issue number5
StatePublished - May 2006
Externally publishedYes


  • Cell therapy
  • Congestive heart failure
  • Ischaemic heart disease
  • Myocardial infarction
  • Progenitor cells
  • Stem cells

ASJC Scopus subject areas

  • Pharmacology
  • Drug Discovery
  • Clinical Biochemistry


Dive into the research topics of 'Stem cells for the ischaemic heart'. Together they form a unique fingerprint.

Cite this