@article{9020de9f635343178311f8365f3de43b,
title = "ST isopotential precordial surface maps in patients with acute myocardial infarction",
abstract = "ST amplitude distributions were studied in 41 patients with acute myocardial infarction by deriving isopotential maps from a 5×7 electrode precordial matrix. Independent data on infarct size and localization were obtained utilizing the technetium 99m stannous pyrophosphate scintigraphic method. The locus of maximal ST elevation was stable for at least two days in 86% of 27 patients with anterior infarction. A single maximum or maximum-minimum was found in 88% but 22% of the patients had multiple maxima and/or minima in at least two maps. Areas of significant ST elevation were often excluded from the precordial matrix. The site of maximal ST elevation correlated with scintigraphic infarct site but was displaced medially in lateral infarction. The relation between infarct size and ΣST elevation was significant and curvilinear. ΣST underestimated size in large anterior infarction. The correlation of the size and the number of sites with ST elevation ≥1.5 mm was weak (r=0.56). The degree of ST abnormality in 14 patients with inferior infarction decreased significantly during the initial 24 hours. The isopotential maps were similar to those obtained in anterior infarction but the polarity was reversed. The results provide limited support for the continued exploration of ST analysis as a clinical method but suggest that sizing methods should be based on total body surface mapping, taking into account the geometry and electrical properties of the torso.",
author = "Murray, {R. Gordon} and Peshock, {Ronald M} and Parkey, {Robert W.} and Bonte, {Frederick J.} and Willerson, {James T.} and Blomqvist, {C. Gunnar}",
note = "Funding Information: Electrocardiography has the potential of providing an earlier estimate of infarct size that currently available biochemical and radionuclear methods?-* Experimental data have shown a relationship between early epicardial ST segment elevation and subsequent myocardial necrosis after coronary artery occlusion. 5 Precordial mapping of the ST segment changes in patients has been used in attempts to estimate the extent of myocardial injury and to evaluate the effect of therapeutic interventions in acute myocardial infarction. 6-12 However, the results of several clinical and electrophysiological studies have raised questions regarding the usefulness and rationale of this technique23-~6 Recent data have indicated that there is a strong and linear correlation between histological infarct From the Adolph and Pauline Weinberger Laboratory for Cardiopulmonary Research and the Moss Heart Center, Department of Internal Medicine, Southwestern Medical School, The University of Texas Health Science Center at Dallas. Supported by grants from NIH (Ischemic Heart Disease Specialized Center of Research HLI 17669), the National Aeronautics and Space Administration (NGR 9026) and the Moss Heart Foundation. Dr. Willerson is an Established Investigator of the American Heart Association. The costs of publication of this article were defrayed in part by the payment of page charges. This article must therefore be hereby marked {"}advertisemenV' in accordance with 18 U.S.C. w1 734 solely to indicate this fact. Reprint requests to: C. Gunnar Blomqvist, M.D., Division of Cardiology, The University of Texas Health Science Center at Dallas, 5323 Harry Hines Boulevard, Dallas, Texas 75235.",
year = "1979",
doi = "10.1016/S0022-0736(79)80045-X",
language = "English (US)",
volume = "12",
pages = "55--64",
journal = "Journal of Electrocardiology",
issn = "0022-0736",
publisher = "Churchill Livingstone",
number = "1",
}