Spontaneous interictal spiking in the awake kindled rat

J. G. Fitz; J. O. McNamara

doi:10.1016/0013-4694(79)90260-8

Spontaneous interictal spiking in the awake kindled rat

J. G. Fitz, J. O. McNamara

Research output: Contribution to journal › Article › peer-review

18 Scopus citations

Abstract

The spontaneous interictal spike (SIS) noted in EEG recordings is a signal of the abnormally excitable behavior of neurons in an epileptic focus. This study provides a detailed, quantitative, temporal and spatial profile of SIS in the amygdaloid kindled rat. The reproducible nature of the development and decline of SIS in kindling provides a useful model for biochemical study of the mechanisms that initiate and regulate SIS.

Original language	English (US)
Pages (from-to)	592-596
Number of pages	5
Journal	Electroencephalography and Clinical Neurophysiology
Volume	47
Issue number	5
DOIs	https://doi.org/10.1016/0013-4694(79)90260-8
State	Published - Nov 1979

ASJC Scopus subject areas

Neuroscience(all)
Clinical Neurology

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10.1016/0013-4694(79)90260-8

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title = "Spontaneous interictal spiking in the awake kindled rat",

abstract = "The spontaneous interictal spike (SIS) noted in EEG recordings is a signal of the abnormally excitable behavior of neurons in an epileptic focus. This study provides a detailed, quantitative, temporal and spatial profile of SIS in the amygdaloid kindled rat. The reproducible nature of the development and decline of SIS in kindling provides a useful model for biochemical study of the mechanisms that initiate and regulate SIS.",

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AB - The spontaneous interictal spike (SIS) noted in EEG recordings is a signal of the abnormally excitable behavior of neurons in an epileptic focus. This study provides a detailed, quantitative, temporal and spatial profile of SIS in the amygdaloid kindled rat. The reproducible nature of the development and decline of SIS in kindling provides a useful model for biochemical study of the mechanisms that initiate and regulate SIS.

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Spontaneous interictal spiking in the awake kindled rat

Abstract

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