Spermidine Promotes Cardioprotective Autophagy

Dan Tong, Joseph A Hill

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


A recent study published in Nature Medicine reports that dietary supplementation with spermidine, a natural polyamine, extends life span and reverses agingassociated cardiac dysfunction in mice through induction of autophagy. Similar protective effects of spermidine on human cardiovascular health were also suggested by epidemiological studies.

Original languageEnglish (US)
Pages (from-to)1229-1231
Number of pages3
JournalCirculation research
Issue number8
StatePublished - Apr 14 2017

ASJC Scopus subject areas

  • Physiology
  • Cardiology and Cardiovascular Medicine


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