Speed congenics: A classic technique in the fast lane (relatively speaking)

Edward Wakeland, Laurence Morel, Karen Achey, Mary Yui, Jeff Longmate

Research output: Contribution to journalComment/debatepeer-review

276 Scopus citations


Marker-assisted selection protocol (MASP)-based strategies produce congenic strains with the target gene contained on clearly defined donor- derived genomic intervals in less than half the number of generations required by the classic protocol. Thus, the quality and speed of congenic strain construction are enhanced by this methodology. Here, Edward Wakeland and colleagues compare various MASP-based strategies and discuss their advantages with reference to immunological traits.

Original languageEnglish (US)
Pages (from-to)472-477
Number of pages6
JournalImmunology Today
Issue number10
StatePublished - Oct 1997

ASJC Scopus subject areas

  • Immunology


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