Specific inhibition of antibody formation by passively administered 19S and 7S antibody

Martin S. Finkelstein; Jonathan W. Uhr

doi:10.1126/science.146.3640.67

Specific inhibition of antibody formation by passively administered 19S and 7S antibody

Martin S. Finkelstein, Jonathan W. Uhr

Immunology

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Intravenously administered 7S antibody is more effective than 19S antibody in inhibiting the formation of antibody to bacteriophage φX174. Since considerable amounts of 7S antibody are needed for inhibition, serum antibody formation may act as a "feedback" mechanism to prevent hyperimmunization.

Original language	English (US)
Pages (from-to)	67-69
Number of pages	3
Journal	Science
Volume	146
Issue number	3640
DOIs	https://doi.org/10.1126/science.146.3640.67
State	Published - 1964

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title = "Specific inhibition of antibody formation by passively administered 19S and 7S antibody",

abstract = "Intravenously administered 7S antibody is more effective than 19S antibody in inhibiting the formation of antibody to bacteriophage φX174. Since considerable amounts of 7S antibody are needed for inhibition, serum antibody formation may act as a {"}feedback{"} mechanism to prevent hyperimmunization.",

author = "Finkelstein, {Martin S.} and Uhr, {Jonathan W.}",

year = "1964",

doi = "10.1126/science.146.3640.67",

language = "English (US)",

volume = "146",

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journal = "Science",

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T1 - Specific inhibition of antibody formation by passively administered 19S and 7S antibody

AU - Finkelstein, Martin S.

AU - Uhr, Jonathan W.

PY - 1964

Y1 - 1964

N2 - Intravenously administered 7S antibody is more effective than 19S antibody in inhibiting the formation of antibody to bacteriophage φX174. Since considerable amounts of 7S antibody are needed for inhibition, serum antibody formation may act as a "feedback" mechanism to prevent hyperimmunization.

AB - Intravenously administered 7S antibody is more effective than 19S antibody in inhibiting the formation of antibody to bacteriophage φX174. Since considerable amounts of 7S antibody are needed for inhibition, serum antibody formation may act as a "feedback" mechanism to prevent hyperimmunization.

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Specific inhibition of antibody formation by passively administered 19S and 7S antibody

Abstract

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