Special Delivery: Granulin Brings CpG DNA to Toll-like Receptor 9

Eva Marie Y Moresco; Bruce Beutler

doi:10.1016/j.immuni.2011.04.001

Special Delivery: Granulin Brings CpG DNA to Toll-like Receptor 9

Eva Marie Y Moresco, Bruce Beutler

Research output: Contribution to journal › Short survey › peer-review

16 Scopus citations

Abstract

Foreign DNA activates the innate immune response through Toll-like receptor 9 (TLR9). In this issue of Immunity, Park et al. (2011) present evidence that granulin is a cofactor for TLR9 activation, delivering CpG-oligodeoxynucleotides to TLR9 in endolysosomes.

Original language	English (US)
Pages (from-to)	453-455
Number of pages	3
Journal	Immunity
Volume	34
Issue number	4
DOIs	https://doi.org/10.1016/j.immuni.2011.04.001
State	Published - Apr 22 2011

ASJC Scopus subject areas

Immunology and Allergy
Immunology
Infectious Diseases

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10.1016/j.immuni.2011.04.001

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title = "Special Delivery: Granulin Brings CpG DNA to Toll-like Receptor 9",

abstract = "Foreign DNA activates the innate immune response through Toll-like receptor 9 (TLR9). In this issue of Immunity, Park et al. (2011) present evidence that granulin is a cofactor for TLR9 activation, delivering CpG-oligodeoxynucleotides to TLR9 in endolysosomes.",

author = "Moresco, {Eva Marie Y} and Bruce Beutler",

year = "2011",

month = apr,

day = "22",

doi = "10.1016/j.immuni.2011.04.001",

language = "English (US)",

volume = "34",

pages = "453--455",

journal = "Immunity",

issn = "1074-7613",

publisher = "Cell Press",

number = "4",

}

TY - JOUR

T1 - Special Delivery

T2 - Granulin Brings CpG DNA to Toll-like Receptor 9

AU - Moresco, Eva Marie Y

AU - Beutler, Bruce

PY - 2011/4/22

Y1 - 2011/4/22

N2 - Foreign DNA activates the innate immune response through Toll-like receptor 9 (TLR9). In this issue of Immunity, Park et al. (2011) present evidence that granulin is a cofactor for TLR9 activation, delivering CpG-oligodeoxynucleotides to TLR9 in endolysosomes.

AB - Foreign DNA activates the innate immune response through Toll-like receptor 9 (TLR9). In this issue of Immunity, Park et al. (2011) present evidence that granulin is a cofactor for TLR9 activation, delivering CpG-oligodeoxynucleotides to TLR9 in endolysosomes.

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U2 - 10.1016/j.immuni.2011.04.001

DO - 10.1016/j.immuni.2011.04.001

M3 - Short survey

C2 - 21511177

AN - SCOPUS:79954611516

SN - 1074-7613

VL - 34

SP - 453

EP - 455

JO - Immunity

JF - Immunity

IS - 4

ER -

Special Delivery: Granulin Brings CpG DNA to Toll-like Receptor 9

Abstract

ASJC Scopus subject areas

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