TY - JOUR
T1 - Society of Dermatology Hospitalists supportive care guidelines for the management of Stevens-Johnson syndrome/toxic epidermal necrolysis in adults
AU - Seminario-Vidal, Lucia
AU - Kroshinsky, Daniela
AU - Malachowski, Stephen J.
AU - Sun, James
AU - Markova, Alina
AU - Beachkofsky, Thomas M.
AU - Kaffenberger, Benjamin H.
AU - Ergen, Elizabeth N.
AU - Mauskar, Melissa
AU - Bridges, Alina
AU - Calhoun, Cody
AU - Cardones, Adela R.
AU - Chen, Steven T.
AU - Chodosh, James
AU - Cotliar, Jonathan
AU - Davis, Mark D.P.
AU - DeNiro, Katherine L.
AU - Dominguez, Arturo R.
AU - Eljure-Téllez, Juliana
AU - Femia, Alisa
AU - Fox, Lindy P.
AU - Guda, Anisha
AU - Mitchell, Caroline
AU - Mostaghimi, Arash
AU - Ortega-Loayza, Alex G.
AU - Owen, Cindy
AU - Pasieka, Helena
AU - Rahnama-Moghadam, Sahand
AU - Saeed, Hajirah N.
AU - Saunderson, Rebecca B.
AU - Shanbhag, Swapna
AU - Sharon, Victoria R.
AU - Strowd, Lindsay
AU - Venkatesh, Samantha
AU - Wanat, Karolyn A.
AU - Wetter, David A.
AU - Worswick, Scott
AU - Micheletti, Robert G.
N1 - Publisher Copyright:
© 2020 American Academy of Dermatology, Inc.
PY - 2020/6
Y1 - 2020/6
N2 - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by dermatologists, ophthalmologists, intensivists, and gynecologists with expertise in SJS/TEN to generate statements for supportive care guideline development. Members of the Society of Dermatology Hospitalists with expertise in SJS/TEN were invited to participate in a modified, online Delphi-consensus. Participants were administered 9-point Likert scale questionnaires regarding 135 statements. The RAND/UCLA Appropriateness Method was used to evaluate and select proposed statements for guideline inclusion; statements with median ratings of 6.5 to 9 and a disagreement index of ≤1 were included in the guideline. For the final round, the guidelines were appraised by all of the participants. Included are an evidence-based discussion and recommendations for hospital setting and care team, wound care, ocular care, oral care, urogenital care, pain management, infection surveillance, fluid and electrolyte management, nutrition and stress ulcer prophylaxis, airway management, and anticoagulation in adult patients with SJS/TEN.
AB - Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are life-threatening conditions with high morbidity and mortality. Supportive care management of SJS/TEN is highly variable. A systematic review of the literature was performed by dermatologists, ophthalmologists, intensivists, and gynecologists with expertise in SJS/TEN to generate statements for supportive care guideline development. Members of the Society of Dermatology Hospitalists with expertise in SJS/TEN were invited to participate in a modified, online Delphi-consensus. Participants were administered 9-point Likert scale questionnaires regarding 135 statements. The RAND/UCLA Appropriateness Method was used to evaluate and select proposed statements for guideline inclusion; statements with median ratings of 6.5 to 9 and a disagreement index of ≤1 were included in the guideline. For the final round, the guidelines were appraised by all of the participants. Included are an evidence-based discussion and recommendations for hospital setting and care team, wound care, ocular care, oral care, urogenital care, pain management, infection surveillance, fluid and electrolyte management, nutrition and stress ulcer prophylaxis, airway management, and anticoagulation in adult patients with SJS/TEN.
KW - Society of Dermatology Hospitalists
KW - Stevens-Johnson syndrome
KW - dermatology consultation
KW - inpatient
KW - severe cutaneous adverse reaction
KW - toxic epidermal necrolysis
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U2 - 10.1016/j.jaad.2020.02.066
DO - 10.1016/j.jaad.2020.02.066
M3 - Article
C2 - 32151629
AN - SCOPUS:85083321705
SN - 0190-9622
VL - 82
SP - 1553
EP - 1567
JO - Journal of the American Academy of Dermatology
JF - Journal of the American Academy of Dermatology
IS - 6
ER -