@inbook{3be8435277af49d6b6d9e96f2ba4f15c,
title = "Signs and Symptoms",
abstract = "The majority of pediatric bone tumors are benign; however, malignant bone tumors account for a signifi cant amount of morbidity and mortality among children and adolescents. Due to their often indolent presentation the diagnosis is often delayed. This chapter will highlight the signs and symptoms of malignant bone tumors including osteosarcoma, Ewing sarcoma, and chondrosarcoma. Malignant bone tumors vary by age, sex, ethnicity and tumor location. The typical presenting symptoms are similar for most malignant bone tumors with a few distinct variations between the subtypes. The initial diagnostic evaluation will be reviewed and subsequent chapters will go into more detail regarding the radiographic and pathologic diagnosis. There are a few syndromes with a known predisposition to malignant bone tumors that will be highlighted.",
author = "Martin, {Andrew A} and Leavey, {Patrick J.}",
note = "Publisher Copyright: {\textcopyright} Springer International Publishing Switzerland 2015.",
year = "2015",
doi = "10.1007/978-3-319-18099-1_1",
language = "English (US)",
series = "Pediatric Oncology",
publisher = "Springer Science and Business Media Deutschland GmbH",
pages = "1--7",
booktitle = "Pediatric Oncology",
address = "Germany",
}