Short-term intensive insulin therapy at diagnosis in type 2 diabetes: Plan for filling the gaps

Jianping Weng, Ravi Retnakaran, Ammini Ariachery C, Linong Ji, Luigi Meneghini, Wenying Yang, Jeong Taek Woo

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Short-term intensive insulin therapy is unique amongst therapies for type 2 diabetes because it offers the potential to preserve and improve beta-cell function without additional pharmacological treatment. On the basis of clinical experience and the promising results of a series of studies in newly diagnosed patients, mostly in Asian populations, an expert workshop was convened to assess the available evidence and the potential application of short-term intensive insulin therapy should it be advocated for inclusion in clinical practice. Participants included primary care physicians and endocrinologists. We endorse the concept of short-term intensive insulin therapy as an option for some patients with type 2 diabetes at the time of diagnosis and have identified the following six areas where additional knowledge could help clarify optimal use in clinical practice: (1) generalizability to primary care, (2) target population and biomarkers, (3) follow-up treatment, (4) education of patients and providers, (5) relevance of ethnicity, and (6) health economics.

Original languageEnglish (US)
Pages (from-to)537-544
Number of pages8
JournalDiabetes/Metabolism Research and Reviews
Issue number6
StatePublished - Sep 1 2015


  • Consensus
  • Short-term intensive insulin therapy
  • Type 2 diabetes

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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