Serum free light chain analysis

Rajeevan Selvaratnam; Jing Cao; Amy B. Karger

doi:10.1007/978-3-319-10918-3_2

Serum free light chain analysis

Rajeevan Selvaratnam, Jing Cao, Amy B. Karger

Research output: Chapter in Book/Report/Conference proceeding › Chapter

2 Scopus citations

Abstract

In healthy individuals, plasma cells originating from the bone marrow produce immunoglobulin molecules composed of two heavy chains and two light chains. There are two types of light chains in humans, kappa and lambda. The chapter provides an overview of the history, utility and interpretation of free light chain (FLC) measurement in plasma cell dyscrasias.

Original language	English (US)
Title of host publication	Plasma Cell Neoplasms
Subtitle of host publication	A Morphologic, Cytogenetic and Immunophenotypic Approach
Publisher	Springer International Publishing
Pages	25-42
Number of pages	18
ISBN (Electronic)	9783319109183
ISBN (Print)	9783319109176
DOIs	https://doi.org/10.1007/978-3-319-10918-3_2
State	Published - Jan 1 2015
Externally published	Yes

ASJC Scopus subject areas

General Medicine

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10.1007/978-3-319-10918-3_2

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title = "Serum free light chain analysis",

abstract = "In healthy individuals, plasma cells originating from the bone marrow produce immunoglobulin molecules composed of two heavy chains and two light chains. There are two types of light chains in humans, kappa and lambda. The chapter provides an overview of the history, utility and interpretation of free light chain (FLC) measurement in plasma cell dyscrasias.",

author = "Rajeevan Selvaratnam and Jing Cao and Karger, {Amy B.}",

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doi = "10.1007/978-3-319-10918-3_2",

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AU - Selvaratnam, Rajeevan

AU - Cao, Jing

AU - Karger, Amy B.

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N2 - In healthy individuals, plasma cells originating from the bone marrow produce immunoglobulin molecules composed of two heavy chains and two light chains. There are two types of light chains in humans, kappa and lambda. The chapter provides an overview of the history, utility and interpretation of free light chain (FLC) measurement in plasma cell dyscrasias.

AB - In healthy individuals, plasma cells originating from the bone marrow produce immunoglobulin molecules composed of two heavy chains and two light chains. There are two types of light chains in humans, kappa and lambda. The chapter provides an overview of the history, utility and interpretation of free light chain (FLC) measurement in plasma cell dyscrasias.

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DO - 10.1007/978-3-319-10918-3_2

M3 - Chapter

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SN - 9783319109176

SP - 25

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BT - Plasma Cell Neoplasms

PB - Springer International Publishing

ER -

Serum free light chain analysis

Abstract

ASJC Scopus subject areas

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