TY - JOUR
T1 - Sensory aspects of movement disorders
AU - Patel, Neepa
AU - Jankovic, Joseph
AU - Hallett, Mark
N1 - Funding Information:
MH is an employee of the National Institutes of Health. JJ acknowledges the support of the National Parkinson Foundation and the Huntington Disease Association of America. NP has received support for a movement disorder fellowship from the Dystonia Medical Research Foundation.
PY - 2014/1
Y1 - 2014/1
N2 - Movement disorders, which include disorders such as Parkinson's disease, dystonia, Tourette's syndrome, restless legs syndrome, and akathisia, have traditionally been considered to be disorders of impaired motor control resulting predominantly from dysfunction of the basal ganglia. This notion has been revised largely because of increasing recognition of associated behavioural, psychiatric, autonomic, and other non-motor symptoms. The sensory aspects of movement disorders include intrinsic sensory abnormalities and the effects of external sensory input on the underlying motor abnormality. The basal ganglia, cerebellum, thalamus, and their connections, coupled with altered sensory input, seem to play a key part in abnormal sensorimotor integration. However, more investigation into the phenomenology and physiological basis of sensory abnormalities, and about the role of the basal ganglia, cerebellum, and related structures in somatosensory processing, and its effect on motor control, is needed.
AB - Movement disorders, which include disorders such as Parkinson's disease, dystonia, Tourette's syndrome, restless legs syndrome, and akathisia, have traditionally been considered to be disorders of impaired motor control resulting predominantly from dysfunction of the basal ganglia. This notion has been revised largely because of increasing recognition of associated behavioural, psychiatric, autonomic, and other non-motor symptoms. The sensory aspects of movement disorders include intrinsic sensory abnormalities and the effects of external sensory input on the underlying motor abnormality. The basal ganglia, cerebellum, thalamus, and their connections, coupled with altered sensory input, seem to play a key part in abnormal sensorimotor integration. However, more investigation into the phenomenology and physiological basis of sensory abnormalities, and about the role of the basal ganglia, cerebellum, and related structures in somatosensory processing, and its effect on motor control, is needed.
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U2 - 10.1016/S1474-4422(13)70213-8
DO - 10.1016/S1474-4422(13)70213-8
M3 - Review article
C2 - 24331796
AN - SCOPUS:84892187093
SN - 1474-4422
VL - 13
SP - 100
EP - 112
JO - The Lancet Neurology
JF - The Lancet Neurology
IS - 1
ER -