@article{d8453ff737654f31a02ce091b2c0a5ac,
title = "Sema3a-Nrp1 Signaling Mediates Fast-Twitch Myofiber Specificity of Tw2+ Cells",
abstract = "Tw2+ cells are an interstitial muscle progenitor population that fuses specifically with fast-twitch myofibers. Li et al. show that the mechanism of fiber-type specificity revolves around a chemorepulsion system mediated by Sema3a and Nrp1 signaling.",
keywords = "Twist2, chemorepulsion, fiber-type specificity, fusion, muscle stem cell, plexin, semaphorin, stripe assay",
author = "Stephen Li and Dileep Karri and Efrain Sanchez-Ortiz and Priscilla Jaichander and Rhonda Bassel-Duby and Ning Liu and Olson, {Eric N.}",
note = "Funding Information: We are grateful to UT Southwestern Flow Cytometry Core Facility, the Moody Foundation Flow Cytometry Facility, and UTSW Genomics and Microarray Core Facility for technical help and service. We thank C. Nolen for technical assistance and Jose Cabrera for graphics assistance. This work was supported by grants from the NIH ( AR-067294 , HL-130253 , HL-138426 , and HD-087351 ) and the Robert A. Welch Foundation (grant 1-0025 to E.N.O.). S.L. was supported by a F30 fellowship from the NIH ( F30AG056075 ). N.L. was supported by a grant from the NIH ( R01AR071980-01A1 ). Funding Information: We are grateful to UT Southwestern Flow Cytometry Core Facility, the Moody Foundation Flow Cytometry Facility, and UTSW Genomics and Microarray Core Facility for technical help and service. We thank C. Nolen for technical assistance and Jose Cabrera for graphics assistance. This work was supported by grants from the NIH (AR-067294, HL-130253, HL-138426, and HD-087351) and the Robert A. Welch Foundation (grant 1-0025 to E.N.O.). S.L. was supported by a F30 fellowship from the NIH (F30AG056075). N.L. was supported by a grant from the NIH (R01AR071980-01A1). Experiments were designed by S.L. and N.L. Experiments were performed by S.L. D.K. E.S.-O. and P.J. Data were interpreted by S.L. D.K. R.B.-D. N.L. and E.N.O. The paper was written and edited by S.L. N.L. R.B.-D. and E.N.O. The authors declare no competing interests. Publisher Copyright: {\textcopyright} 2019 Elsevier Inc.",
year = "2019",
month = oct,
day = "7",
doi = "10.1016/j.devcel.2019.08.002",
language = "English (US)",
volume = "51",
pages = "89--98.e4",
journal = "Developmental cell",
issn = "1534-5807",
publisher = "Cell Press",
number = "1",
}