Abstract
Sec61p/SecYEG complexes mediate protein translocation across membranes and are present in both eukaryotes and bacteria. Whereas homologues of Sec61α/SecY and Sec61γ/SecE exist in archaea, identification of the third component (Sec61β or SecG) has remained elusive. Using PSI-BLAST, the archaeal counterpart of Sec61β has been detected. With the identification of the Sec61β motif, functions for a universal family of archaeal proteins can be predicted and the archaeal translocon system can be definitively detected.
Original language | English (US) |
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Pages (from-to) | 170-171 |
Number of pages | 2 |
Journal | Trends in biochemical sciences |
Volume | 27 |
Issue number | 4 |
DOIs | |
State | Published - Apr 1 2002 |
ASJC Scopus subject areas
- Biochemistry
- Molecular Biology