Sciatic nerve tumor and tumor-like lesions-uncommon pathologies

Vibhor Wadhwa, Rashmi S. Thakkar, Nicholas Maragakis, Ahmet Höke, Charlotte J. Sumner, Thomas E. Lloyd, John A. Carrino, Allan J. Belzberg, Avneesh Chhabra

Research output: Contribution to journalReview articlepeer-review

42 Scopus citations


Sciatic nerve mass-like enlargement caused by peripheral nerve sheath tumors or neurocutaneous syndromes such as neurofibromatosis or schwannomatosis has been widely reported. Other causes of enlargement, such as from perineuroma, fibromatosis, neurolymphoma, amyloidosis, endometriosis, intraneural ganglion cyst, Charcot-Marie-Tooth disease, and chronic inflammatory demyelinating polyneuropathy are relatively rare. Highresolution magnetic resonance imaging (MRI) is an excellent non-invasive tool for the evaluation of such lesions. In this article, the authors discuss normal anatomy of the sciatic nerve and MRI findings of the abovementioned lesions.

Original languageEnglish (US)
Pages (from-to)763-774
Number of pages12
JournalSkeletal radiology
Issue number7
StatePublished - Jul 2012


  • Amyloidosis
  • Charcot-Marie-Tooth disease
  • Chronic inflammatory demyelinating polyneuropathy
  • Endometriosis
  • Fibromatosis
  • Intraneural ganglion
  • Lymphoma
  • Magnetic resonance imaging
  • Perineurioma
  • Sciatic nerve

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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