Same specimen, different diagnoses: Suprahistologic elements in observer variability

Robert M. Genta

Research output: Contribution to journalReview articlepeer-review

6 Scopus citations


External influences, referred to as suprahistologic elements, may modulate pathologists' interpretation of morphologic findings. These elements can be divided into those that are loosely evidence based and exert a desirable influence on the diagnosis and those that arise from emotional, sometimes irrational perceptions not rooted in objective evidence. The latter, together with individual experience and competence, may lie at the core of the notorious interobserver and intraobserver variability.

Original languageEnglish (US)
Pages (from-to)188-190
Number of pages3
JournalAdvances in anatomic pathology
Issue number3
StatePublished - May 2014


  • diagnosis
  • evidence-based practice
  • histopathology

ASJC Scopus subject areas

  • Anatomy
  • Pathology and Forensic Medicine


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