TY - JOUR
T1 - Rosai-Dorfman disease of the gastrointestinal tract
T2 - Report of a case and review of the literature
AU - Alatassi, Houda
AU - Ray, Mukunda B.
AU - Galandiuk, Susan
AU - Sahoo, Sunati
PY - 2006/1/1
Y1 - 2006/1/1
N2 - Rosai-Dorfman disease (RDD) is a rare, acquired disease of unknown etiology that affects primarily chifdren and young adults. It is characterized by a proliferation of distinctive histiocytes in the lymph nodes and/or extranodal sites, involvement of the gastrointestinal tract is rare. We report a case of RDD in a 60-year-old woman who presented with hematochezia and was found to have RDD of the rectum presenting as a rectal mass. This report highlights the current pathogenetic mechanisms, immunohistochemical markers, and the gastrointestinal manifestations of RDD.
AB - Rosai-Dorfman disease (RDD) is a rare, acquired disease of unknown etiology that affects primarily chifdren and young adults. It is characterized by a proliferation of distinctive histiocytes in the lymph nodes and/or extranodal sites, involvement of the gastrointestinal tract is rare. We report a case of RDD in a 60-year-old woman who presented with hematochezia and was found to have RDD of the rectum presenting as a rectal mass. This report highlights the current pathogenetic mechanisms, immunohistochemical markers, and the gastrointestinal manifestations of RDD.
KW - Gastrointestinal tract
KW - Rosai-Dorfman disease
KW - Sinus histiocytosis with massive lymphadenopathy
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U2 - 10.1177/106689690601400119
DO - 10.1177/106689690601400119
M3 - Review article
C2 - 16501845
AN - SCOPUS:32344449311
SN - 1066-8969
VL - 14
SP - 95
EP - 99
JO - International Journal of Surgical Pathology
JF - International Journal of Surgical Pathology
IS - 1
ER -