Role of virtual biopsy in the management of renal masses

Alberto Diaz De Leon, Matthew S. Davenport, Stuart G. Silverman, Nicola Schieda, Jeffrey A. Cadeddu, Ivan Pedrosa

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


OBJECTIVE. Renal masses comprise a heterogeneous group of pathologic conditions, including benign and indolent diseases and aggressive malignancies, complicating management. In this article, we explore the emerging role of imaging to provide a comprehensive noninvasive characterization of a renal mass so-called "virtual biopsy" and its potential use in the management of patients with renal tumors. CONCLUSION. Percutaneous renal mass biopsy (RMB) remains a valuable method to provide a presurgical histopathologic diagnosis of renal masses, but it is an invasive procedure and is not always feasible. Accumulating data support the use of imaging features to predict histopathology of renal masses. Imaging may help address some of the inherent limitations of RMB, and in certain settings, a multimodal clinical approach may allow decreasing the need for RMB.

Original languageEnglish (US)
Pages (from-to)1234-1243
Number of pages10
JournalAmerican Journal of Roentgenology
Issue number6
StatePublished - Jun 2019


  • CT
  • MRI
  • Renal cell carcinoma
  • Renal mass
  • Renal mass biopsy

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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