Role of 3 tesla mr neurography and CT-guided injections for pudendal neuralgia: analysis of pain response

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6 Scopus citations


Background: Magnetic resonance neurography (MRN) has an increasing role in the diagnosis and management of pudendal neuralgia, a neurogenic cause of chronic pelvic pain. Objective: The objective of this research was to determine the role of MRN in predicting improved pain outcomes following computed tomography (CT)-guided perineural injections in patients with pudendal neuralgia. Study Design: This study used a retrospective cross-sectional study design. Setting: The research was conducted at a large academic hospital. Methods: Patients: Ninety-one patients (139 injections) who received MRN and CT-guided pudendal blocks were analyzed. Intervention: A 3Tesla (T) scanner was used to evaluate the lumbosacral plexus for pudendal neuropathy. Prior to receiving a CT-guided pudendal perineural injection, patients were given pain logs and asked to record pain on a visual analog scale. Measurement: MRN findings for pudendal neuropathy were compared to the results of the CTguided pudendal nerve blocks. Injection pain responses were categorized into 3 groups – positive block, possible positive block, and negative block. Statistical Tests: A chi-square test was used to test any association, and a Cochran-Armitage trend test was used to test any trend. Significance level was set at.05. All analyses were done in SAS Version 9.4 (SAS Institute, Inc., Cary, NC). Results: Ninety-one patients (139 injections) who received MRN were analyzed. Of these 139 injections, 41 were considered positive (29.5%), 52 of 139 were possible positives (37.4%), and 46 of 139 were negative blocks (33.1%). Of the patients who had a positive pudendal block, no significant difference was found between the MRN result and the pudendal perineural injection response (P =.57). Women had better overall response to pudendal blocks, but this response was not associated with MRN findings (P =.34). However, positive MRN results were associated with better pain response in men (P =.005). Patients who reported bowel dysfunction also had a better response to pudendal perineural injection (P =.02). Limitations: Some limitations include subjectivity of pain reporting, reporting consistency, absence of a control group, and the retrospective nature of the chart review. Conclusion: Pudendal perineural injections improve pain in patients with pudendal neuralgia and positive MRN results are associated with better response in men.

Original languageEnglish (US)
Pages (from-to)E333-E344
JournalPain physician
Issue number4
StatePublished - Jul 1 2019


  • CT injection
  • MRI
  • MRN
  • chronic pelvic pain
  • pelvic pain
  • pudendal nerve
  • pudendal neuralgia
  • pudendal neuropathy

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine


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