Rhythmic variations of valine and leucine decarboxylation in rat diaphragm

Dorothy A. Potter, Stephen Gene Sullivan, Rody P. Cox

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Daily rhythmic variations of valine and leucine decarboxylation in the rat diaphragm were measured. Both valine and leucine decarboxylation increased during the hours of darkness and decreased during hours of light. Hypophysectomy eliminated the daily variation of decarboxylation. When food is available ad lib. to normal rats, the time of most active feeding coincides with the hours of darkness. Therefore, the period of darkness and maximum feeding coincides with the maximum oxidation of these two essential amino acids, valine and leucine, by diaphragm, and an active pituitary appears to be necessary to maintain this relationship. This model can be used to study interrelationships of behavioral, neurohumoral, and metabolic rhythms.

Original languageEnglish (US)
Pages (from-to)435-437
Number of pages3
Issue number5
StatePublished - May 1980

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology


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