Restoration of the coagulation cascade on CPB: A case report

K. J. Lilly, P. A. Pirundini, A. A. Fox, S. C. Body, C. Shaw, R. J. Rizzo

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Coagulopathy can sometimes be observed when CPB times are prolonged. Correction of coagulopathy post CPB can present the surgical team with a number of challenges, including right ventricular volume overload, hemodilution, anemia and excessive cell salvage with further loss of coagulation factors. Restoration of the coagulation cascade on CPB may help to avoid these issues. This case report is of a 64-year-old male with a delayed diagnosis of aortic dissection. The patient presented to the cardiac surgery operating room with hepatic and renal shock/failure, with the resulting coagulopathy. The described technique is representative of a technique that we sometimes employ to restore the clotting mechanism before separating from bypass.

Original languageEnglish (US)
Pages (from-to)272-274
Number of pages3
JournalPerfusion (United Kingdom)
Issue number3
StatePublished - May 2014


  • ACT decoupling: hemoconcentration
  • coagulopathy
  • fresh frozen plasma (FFP)

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Safety Research
  • Cardiology and Cardiovascular Medicine
  • Advanced and Specialized Nursing


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