Abstract
Purpose of reviewSurgery for renal cell carcinoma (RCC) with inferior vena cava tumor thrombus (TT) remains one of the most complex surgeries performed with high rates of associated complications and perioperative mortality. Surgical techniques and neoadjuvant therapies have an important role to play in improving outcomes. This review provides a narrative analysis of recent literature on patients with RCC and TT.Recent findingsSeveral imaging techniques are emerging that may improve diagnostic staging of tumor thrombus level. Robotic approaches to surgical resection for all thrombi levels is feasible and safe, while longer term outcomes for higher level thrombi continues to mature. Early data on neoadjuvant immunotherapy and radiotherapy have shown improvements in complication rates and intermediate term oncologic outcomes.SummaryData suggests that neoadjuvant therapies and minimally invasive techniques may improve outcomes in patients undergoing surgical resection for RCC with tumor thrombus. Larger multiinstitutional series are needed to confirm the benefit of these techniques as well as the durable long term oncologic outcomes.
Original language | English (US) |
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Pages (from-to) | 142-146 |
Number of pages | 5 |
Journal | Current opinion in urology |
Volume | 33 |
Issue number | 2 |
DOIs | |
State | Published - Mar 1 2023 |
Keywords
- carcinoma renal cell
- outcomes
- surgical resection
- thrombectomy
- vena cava inferior
ASJC Scopus subject areas
- Urology