Abstract
Background: Minimal data are available on the relationship between asthma and cognitive performance. In this report, we examine the relationship between asthma and cognitive performance in older adults, a subpopulation with elevated risk of cognitive impairment. Methods: We conducted a cross-sectional, retrospective analysis of 1380 participants age ≥55 who completed preventive health examinations at the Cooper Clinic in Dallas, TX. Cognition was assessed using the Montreal Cognitive Assessment (MoCA), a brief test for mild cognitive impairment. Data were analyzed in a multiple logistic regression using MoCA scores suggestive of cognitive impairment as the dependent variable. Results: When controlling for demographic characteristics, self-rated health status, inhaled corticosteroid use, and FEV1/FVC, asthma were associated with 78% increased risk of cognitive impairment (P = 0.02) as defined by MoCA score. Conclusions: In the largest sample examined to date, we have identified a significant relationship between asthma and cognitive impairment in older people.
Original language | English (US) |
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Pages (from-to) | 545-548 |
Number of pages | 4 |
Journal | Allergy: European Journal of Allergy and Clinical Immunology |
Volume | 68 |
Issue number | 4 |
DOIs | |
State | Published - Apr 2013 |
Keywords
- asthma
- cognition
- corticosteroid
- elderly
- spirometry
ASJC Scopus subject areas
- Immunology and Allergy
- Immunology