TY - GEN
T1 - Relation between arterial blood pressure and cerebral blood flow velocity in simulated sleep apnea
AU - Hassan, Gedaa
AU - Alex, Raichel
AU - Bhave, Gauri
AU - Al-Abed, Mohammad A.
AU - Bashaboyina, Aditya
AU - Iyer, Swathi
AU - Watenpaugh, Donald E.
AU - Zhang, Rong
AU - Behbehani, Khosrow
N1 - Copyright:
Copyright 2013 Elsevier B.V., All rights reserved.
PY - 2012
Y1 - 2012
N2 - Obstructive Sleep Apnea (OSA) is one of the most common breathing disorder, affecting approximately 27% of U.S. adults. Limited data have suggested that OSA causes cerebral autoregulation impairment, thus being an important risk factor to stroke. The objective of this paper is to investigate and measure the relation between arterial blood pressure (BP) and cerebral blood flow velocity (CBFV) in simulated apnea. Sixteen healthy subjects (9 male, 7 female) of 29±4.89 yrs age and body mass index of 24.07±4.84 kg/m2 participated in the study. Four protocols were used; sitting 30 seconds, 90s, and supine 30s and 90s. Our results showed that systolic BP and peak CBFV were correlated with average r=0.672 +0.265. Also, CBFV exhibited a significantly higher percent rise than BP. Thus, our findings suggest that cerebral autoregulation may be impaired during apnea episodes.
AB - Obstructive Sleep Apnea (OSA) is one of the most common breathing disorder, affecting approximately 27% of U.S. adults. Limited data have suggested that OSA causes cerebral autoregulation impairment, thus being an important risk factor to stroke. The objective of this paper is to investigate and measure the relation between arterial blood pressure (BP) and cerebral blood flow velocity (CBFV) in simulated apnea. Sixteen healthy subjects (9 male, 7 female) of 29±4.89 yrs age and body mass index of 24.07±4.84 kg/m2 participated in the study. Four protocols were used; sitting 30 seconds, 90s, and supine 30s and 90s. Our results showed that systolic BP and peak CBFV were correlated with average r=0.672 +0.265. Also, CBFV exhibited a significantly higher percent rise than BP. Thus, our findings suggest that cerebral autoregulation may be impaired during apnea episodes.
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U2 - 10.1109/EMBC.2012.6347446
DO - 10.1109/EMBC.2012.6347446
M3 - Conference contribution
C2 - 23367381
AN - SCOPUS:84870830179
SN - 9781424441198
T3 - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
SP - 6349
EP - 6352
BT - 2012 Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2012
T2 - 34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
Y2 - 28 August 2012 through 1 September 2012
ER -