Abstract
The regulation of the guidance receptor plexin is incompletely understood. In this issue, Kong et al. (2016) present crystal structures of the full-length extracellular region of class A plexins, revealing its dual role in both autoinhibition and activation.
Original language | English (US) |
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Pages (from-to) | 497-499 |
Number of pages | 3 |
Journal | Neuron |
Volume | 91 |
Issue number | 3 |
DOIs | |
State | Published - Aug 3 2016 |
Keywords
- activation
- autoinhibition
- axon guidance
- dimerization
- plexin
- structure
ASJC Scopus subject areas
- General Neuroscience