Regulation of clock genes

Y. Liu, C. Heintzen, J. Loros, J. C. Dunlap

Research output: Contribution to journalReview articlepeer-review

16 Scopus citations


A recent explosion in the identification of new clock components in cyanobacteria, fungi, insects, mammals as well as potential candidates in plants has uncovered common themes among the structure, function and regulation of these components. Positive and negative interactions that are organized in negative feedback loops have been found crucial for clock function. Both transcriptional and posttranscriptional mechanisms appear to be important for circadian rhythm generation in all of these organisms.

Original languageEnglish (US)
Pages (from-to)1195-1205
Number of pages11
JournalCellular and Molecular Life Sciences
Issue number10
StatePublished - Aug 15 1999


  • Circadian
  • Drosophila
  • Mouse
  • Neurospora
  • frq
  • per

ASJC Scopus subject areas

  • Molecular Medicine
  • Molecular Biology
  • Pharmacology
  • Cellular and Molecular Neuroscience
  • Cell Biology


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