A direct exhaustive reduction of aliphatic carbonyl functions (aldehydes, acyl chlorides, esters and carboxylic acids) to a methyl group by triethylsilane (Et3SiH) in the presence of catalytic amount of tris(pentafluorophenyl)borane [B(C6F5)3] is described. Aromatic carbonyl functions could undergo partial reduction to the corresponding TES-protected benzylic alcohols.
|Original language||English (US)|
|Number of pages||4|
|State||Published - Feb 2 2004|
- Acyl chlorides
- Carboxylic acids
ASJC Scopus subject areas
- Organic Chemistry