Rectal radiation dose-reduction techniques in prostate cancer: A focus on the rectal spacer

Andrew J. Leiker, Neil B Desai, Michael R Folkert

Research output: Contribution to journalReview articlepeer-review

11 Scopus citations


Prostate cancer is the most common cancer in men. External beam radiotherapy by a variety of methods is a standard treatment option with excellent disease control. However, acute and late rectal side effects remain a limiting concern in intensification of therapy in higher-risk patients and in efforts to reduce treatment burden in others. A number of techniques have emerged that allow for high-radiation dose delivery to the prostate with reduced risk of rectal toxicity, including image-guided intensity-modulated radiation therapy, endorectal balloons and various forms of rectal spacers. Image-guided radiation therapy, either intensity-modulated radiation therapy or stereotactic ablative radiation therapy, in conjunction with a rectal spacer, is an efficacious means to reduce acute and long-term rectal toxicity.

Original languageEnglish (US)
Pages (from-to)2773-2788
Number of pages16
JournalFuture Oncology
Issue number26
StatePublished - Nov 2018


  • endorectal balloon
  • erectile dysfunction
  • prostate cancer
  • radiation therapy
  • rectal spacer
  • rectal toxicity
  • stereotactic ablative radiotherapy
  • stereotactic body radiotherapy

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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