TY - JOUR
T1 - Reassessing the effects of simple carbohydrates on the serum triglyceride responses to fat meals
AU - Cohen, J. C.
AU - Schall, R.
PY - 1988/1/1
Y1 - 1988/1/1
N2 - The effects of glucose, sucrose, and fructose ingestion on the serum triglyceride responses to meals containing 40 g fat were studied in 21 normolipidemic, nonobese medical students (9 men, 12 women). Mean postprandial lipemia was not significantly lower after meals containing 50 g glucose and 40 g fat than after meals containing 40 g fat alone (2.11 vs 2.42 mmol · L-1 · 7 h-1, p > 0.45) despite a substantial increase in plasma insulin concentrations after the glucose-containing meal. Ingestion of 50 g fructose and 40 g fat (4.23 mmol · L-1 · 7 h-1, p < 0.0001) and 100 g sucrose and 40 g fat (3.77 mmol · L-1 · 7 h-1, p < 0.001) resulted in significantly greater lipemia than did the ingestion of fat alone. These findings suggest that the ingestion of insulinogenic carbohydrates does not reduce postprandial lipemia in normolipidemic subjects and that the ingestion of fructose and fructose-containing carbohydrates may augment the postprandial lipemia induced by a fat-containing meal.
AB - The effects of glucose, sucrose, and fructose ingestion on the serum triglyceride responses to meals containing 40 g fat were studied in 21 normolipidemic, nonobese medical students (9 men, 12 women). Mean postprandial lipemia was not significantly lower after meals containing 50 g glucose and 40 g fat than after meals containing 40 g fat alone (2.11 vs 2.42 mmol · L-1 · 7 h-1, p > 0.45) despite a substantial increase in plasma insulin concentrations after the glucose-containing meal. Ingestion of 50 g fructose and 40 g fat (4.23 mmol · L-1 · 7 h-1, p < 0.0001) and 100 g sucrose and 40 g fat (3.77 mmol · L-1 · 7 h-1, p < 0.001) resulted in significantly greater lipemia than did the ingestion of fat alone. These findings suggest that the ingestion of insulinogenic carbohydrates does not reduce postprandial lipemia in normolipidemic subjects and that the ingestion of fructose and fructose-containing carbohydrates may augment the postprandial lipemia induced by a fat-containing meal.
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U2 - 10.1093/ajcn/48.4.1031
DO - 10.1093/ajcn/48.4.1031
M3 - Article
C2 - 3048075
AN - SCOPUS:0023791044
SN - 0002-9165
VL - 48
SP - 1031
EP - 1034
JO - American Journal of Clinical Nutrition
JF - American Journal of Clinical Nutrition
IS - 4
ER -